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For the prevention of relapse of duodenal ulcer in H. pylori negative patients or when H. pylori eradication is not possible the recommended dose is omeprazole 20 mg once daily. In some patients a daily dose of 10 mg may be sufficient. In most patients healing occurs within two weeks.

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Omeprazole decreases stomach acid production which promotes the healing of gastric and duodenal ulcers and other inflamed gastrointestinal tissue areas. Omeprazole is best used short-term. For a complete list of all side effects, click here. The risk of interactions with omeprazole is greater than class action suit against omeprazole other PPIs such as lansoprazole and pantoprazole.

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The mechanism responsible for hypomagnesemia associated with long-term use of proton-pump inhibitors is unknown; however, long-term use of these agents may be associated with changes in intestinal absorption of magnesium. 38 cases from the Adverse Event Reporting SystemAERSdatabase, 23 cases from the medical literatureat least 8 of which have been identified in AERS) FDA confirmed that long-term use (in most cases, longer than one year) of proton-pump inhibitors may be associated with an increased risk of hypomagnesemia; the incidence of this adverse effect could not be quantified because hypomagnesemia is likely underrecognized and underreported. ...

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Omeprazole is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid) Omeprazole may also be given together with antibiotics to treat gastric ulcer caused by infection with Helicobacter pylori (H. Omeprazole is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions caused by excess stomach acid. ...

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Dr Han is Director of the Motherisk Program at Samsung Cheil Hospital, Sungkyunkwan University School of Medicine, in Seoul, Korea. Applying this rule to PPIs makes omeprazole the drug of choice for now. Motherisk questions are prepared by the Motherisk Team at the Hospital for Sick Children in Toronto, Ont. Dr Nava-Ocampo and Ms Vel zquez-Armenta are fellows and Dr Koren is Director of the Motherisk Program. ...

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