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Most of the patients in whom these events have been reported had pre-existing cardiovascular risk factors. However, it is not possible to definitively determine whether these events are related directly to these risk factors, to vardenafil, to sexual activity, or to a combination of these or other factors. Serious cardiovascular events including sudden death, tachycardia, myocardial infarction, ventricular tachy-arrythmia, angina pectoris, and cerebrovascular disorders (including transient ischaemic attack and cerebral haemorrhage) have been reported in temporal association with vardenafil. ...
Of patients on placebo. of patients treated with LEVITRA and 1. ...
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Because alcohol can make it more difficult to get anerection, do not drink large amounts of alcohol before sexual activity. Many things can affect the dose of a medication that aperson needs, such as body weight, other medical conditions, and othermedications. If your doctor has recommended a dose different from the oneslisted here, do not change the way that you are taking the medicationwithout consulting your doctor. ...
Data sources include IBM Watson Micromedex (updated 10 Aug 2020) Cerner Multum (updated 3 Aug 2020) Wolters Kluwer (updated 10 Aug 2020) andothers. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. ...
Discuss with patients the potential cardiac risk of sexual activity for patients with preexisting cardiovascular risk factors. Inform patients that in some patients concomitant use of PDE5 inhibitors, including LEVITRA, with alpha-blockers can lower blood pressure significantly leading to symptomatic hypotension (for example, fainting) Patients prescribed LEVITRA who are taking alpha-blockers should be started on the lowest recommended starting dose of LEVITRAsee DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS. Inform patients that Levitra is contraindicated in patients who use guanylate cyclase stimulators, such as riociguat. ...
It is not possible to determine whether these events were related directly to the use of PDE5 inhibitors or to other factors. Such an event may be a sign of non-arteritic anterior ischemic optic neuropathy (NAION) a cause of decreased vision, including permanent loss of vision, that has been reported rarely post-marketing in temporal association with the use of all PDE5 inhibitors. ...
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