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For the prevention of relapse of duodenal ulcer in H. pylori negative patients or when H. pylori eradication is not possible the recommended dose is omeprazole 20 mg once daily. In some patients a daily dose of 10 mg may be sufficient. In most patients healing occurs within two weeks.

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Omeprazole decreases stomach acid production which promotes the healing of gastric and duodenal ulcers and other inflamed gastrointestinal tissue areas. Omeprazole is best used short-term. For a complete list of all side effects, click here. The risk of interactions with omeprazole is greater than class action suit against omeprazole other PPIs such as lansoprazole and pantoprazole.

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The mechanism responsible for hypomagnesemia associated with long-term use of proton-pump inhibitors is unknown; however, long-term use of these agents may be associated with changes in intestinal absorption of magnesium. 38 cases from the Adverse Event Reporting SystemAERSdatabase, 23 cases from the medical literatureat least 8 of which have been identified in AERS) FDA confirmed that long-term use (in most cases, longer than one year) of proton-pump inhibitors may be associated with an increased risk of hypomagnesemia; the incidence of this adverse effect could not be quantified because hypomagnesemia is likely underrecognized and underreported. ...

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Blood, urine, and other laboratory tests may be needed to check for unwanted effects. Tell your doctor if you are of Asian descent, such as Filipino, Chinese, Japanese, Korean, or Taiwanese. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. ...

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Dr Han is Director of the Motherisk Program at Samsung Cheil Hospital, Sungkyunkwan University School of Medicine, in Seoul, Korea. Applying this rule to PPIs makes omeprazole the drug of choice for now. Motherisk questions are prepared by the Motherisk Team at the Hospital for Sick Children in Toronto, Ont. Dr Nava-Ocampo and Ms Vel zquez-Armenta are fellows and Dr Koren is Director of the Motherisk Program. ...

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